Get to know CBC — the overlooked member of the cannabinoid pack!

CBC rediscovered

CBC (cannabichromene) is one of the four main cannabinoids naturally occurring in cannabis, alongside CBD, THC and CBG. Although it has been known since 1966, when it was discovered by scientists Raphael Mechoulam and Yehiel Gaoni at the Hebrew University of Jerusalem in Israel, it has long been overlooked. What we know about it today is based on the first detailed studies from the 1980s.

However, growing interest in the biodiversity of the cannabis wilderness is now motivating further expeditions and more thorough research into previously overlooked creatures 🏞️. This is bringing new insights into CBC, which you can also find in our zoo

So what do we know about CBC?

How CBC comes into the world

CBC, like its siblings THC and CBD, is born from the parent cannabinoid CBGA (cannabigerolic acid). The enzymatic action of CBCA synthase on CBGA produces CBCA (cannabichromenic acid), from which the carboxyl group is removed by heat — and CBC is born ✨!

CBG as the wolf mother of cannabinoids with three wolf cubs. CBC, CBD, THC, Canabizoo logo at the bottom right.

CBC in the human body

As there are not yet enough studies, we do not know exactly how CBC behaves when it enters the human body. We do know that it primarily interacts with TRPA1 receptors, which are found in nerve cells and help the body respond to various stimuli. Like other cannabinoids, it also acts on the endocannabinoid system (ECS) 🌿. 

The ECS can be thought of as a complex ecosystem full of plants and animals. It is composed of endocannabinoids, receptors and enzymes and regulates various processes in the body — from mood to immune response. 

Like its siblings, CBC appears to have antidepressant, analgesic, anti-inflammatory and neuroprotective properties. Research has also confirmed its strong antibacterial and mild antifungal properties. It is not psychoactive.

The ECS as an ecosystem: a forest with animals and a network of endocannabinoids, receptors and enzymes, CannabiZoo logo at the bottom right

Antidepressant properties

According to studies, CBC can have an antidepressant effect in lower doses and, in higher doses, can calm the body and lower body temperature

It has also been shown not to cause muscle stiffness, which is a common side effect of antidepressants.

Pain and inflammation fighter

Research suggests that CBC has significant anti-inflammatory properties. The results of the study showed that CBC is even more effective against inflammation than some common anti-inflammatory drugs, such as phenylbutazone.

Brain protector

Like most other cannabinoids, CBC has been shown to promote the formation and health of nerve cells, and thus could offer new possibilities in the field of neurodegenerative diseases such as Alzheimer's or Parkinson's disease.

What makes CBC unique?

The unique property of CBC is primarily its ability to positively influence digestion without any undesirable effects.

It can moderate excessive bowel motility, thereby improving nutrient absorption and relieving problems associated with poor digestion, such as cramps and diarrhoea.

This may be important not only in terms of potential new solutions for digestive tract diseases such as Crohn's disease or irritable bowel syndrome, but also in terms of overall support for the body — a healthy tummy means a healthy coat 🐻‍❄️.

CBC in a pack with other cannabinoids 🐺

Cannabinoids can work synergistically together, just like wolves in a pack 🐺. This synergy is called the entourage effect. They complement and reinforce each other's properties, offering comprehensive support

This is why broad spectrum and full spectrum cannabis products, which contain not just one isolated cannabinoid but several, are so popular.

CBC vs. CBD, THC and CBG

Although many cannabinoids share the same effects, each one excels in something different. Below you will find a clear table with the key properties that have been identified in studies to date.

Cannabinoid Most commonly mentioned in connection with Other areas of scientific interest
CBC Digestion Antibacterial activity
CBD well-being and lifestyle epilepsy treatment
THC psychoactivity study of effects on the central nervous system
CBG digestion positive effect on the urinary tract

CBC, CBD, THC and CBG: the four main cannabinoids in cannabis, like wolves sitting in a row, with the CanabiZoo logo at the bottom right.

What can you find at the CBC souvenir stand?

Although CBC is not yet as popular as its siblings, it is found in a wide range of products. 

Among the most popular are CBC vapes. These compact electronic devices can instantly convert cannabinoid-containing liquid into vapour — for example, with Lemonade Kush or Mai Tai flavours.

Cannabinoid oils are popular for their discreet and flexible dosing and use.

  • For fast-acting effects, simply drip under the tongue, where they are quickly absorbed into the bloodstream through the mucous membrane.
  • For support during the day: ideal for mixing into drinks or food.

Want to experience CBC in its most potent form 🦁? Then reach for CBC isolate — a pure cannabichromene extract.

A cheerful, relaxed bear with CBC products: 5% CBC Euphoria oil, CBC CanaPuff vapes, CanabiZoo logo at the bottom right.

CBC: the unjustly neglected member of the cannabinoid quartet

CBC is the most overlooked of the most common cannabinoids, yet it has unique properties. It shares possible antidepressant, analgesic, anti-inflammatory and neuroprotective effects with its counterparts. 

It is unique in its ability to regulate bowel movements, thereby relieving digestive problems.

CBC products are becoming increasingly popular — these include vapes, oils and isolates

FAQ

1. Is CBC legal?

It depends on the region. In most countries in Europe and North America, non-psychoactive cannabinoids are tolerated. They are less accepted or completely banned in Eastern Europe, South America, Africa and Asia. 

2. Is CBC safe?

CBC does not bite! The substance is generally well tolerated without significant side effects and is considered safe.

3. How much CBC per day?

Due to limited research on humans to date, there is no recommended daily intake for CBC and no standardised recommended daily dosage has been established. However, based on the doses tested during research, it can be inferred that approximately 5-10 mg per day is a low dose and 20 mg is a high dose.

4. What are the biggest advantages of CBC over CBD?

CBC has stronger antimicrobial effects and a positive effect on bowel motility, without any undesirable side effects. CBD, on the other hand, excels in its potential positive effects on the psyche.

   

Sources:

  

Author: Natálie Kubíčková

   

   

Photo: AI

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